2007-01-18

2006-03-27

Introduction: Systemic lupus erythematosus (SLE) is a relapsing and remitting multiorgan disease associated with significant morbidity and mortality. The survival rate of patients with SLE has recently improved, which was associated with increased morbidity and hospitalization rates. Systemic lupus erythematosus (SLE) is a chronic multi-organ debilitating autoimmune disease, which mainly afflicts women in the reproductive years. A complex interaction of genetics, environmental factors and hormones result in the breakdown of immune tolerance to "self" leading to damage and destruction of multiple organs, such as the skin, joints, kidneys, heart and brain.

Objective: To study SLE risk, manifestations and severity in relation to urban versus rural residence. PubMed PMID: 27730061; PubMed Central PMCID: PMC5038126. 12: Drehmer MN, Andrade D, Pereira IA, Marrero AR, Muniz YC, de Souza IR, Löfgren SE. Estrogen receptor alpha gene (ESR1) polymorphism can contribute to clinical findings in systemic lupus erythematosus patients. Lupus.

Lupus erythematosus is a collection of autoimmune diseases in which the human immune system becomes hyperactive and attacks healthy tissues. Symptoms of these diseases can affect many different body systems, including joints, skin, kidneys, blood cells, heart, and lungs.

2021-04-02 · Systemic lupus erythematosus (SLE) is an autoimmune disease. In this disease, the immune system of the body mistakenly attacks healthy tissue.

Systemic lupus erythematosus (SLE), an autoimmune disorder which primarily affects women (10:1 female to male ratio), may affect virtually any organ.1 Predominant manifestations include non-deforming arthritis, serositis, photosensitivity, renal, haematological, and central nervous system involvement.

BACKGROUND: Patients with systemic lupus erythematosus seem to belong to different serological and clinical subgroups of the disease. Systemic lupus erythematosus (SLE), is the most common type of lupus.

Women of childbearing age and certain racial groups are typically predisposed to developing the condition. Studies of the immunopathogenesis of systemic lupus erythematosus (SLE) have traditionally focused on the mechanisms of generation of the characteristic autoantibodies reactive with nucleic acid-containing intracellular particles and the contribution of autoantibody-autoantigen immune complexes to the inflammation and tissue damage that result in the clinical manifestations of lupus. PubMed PMID: 27014968. 10: Banovic F, Linder KE, Uri M, Rossi MA, Olivry T. Clinical and microscopic features of generalized discoid lupus erythematosus in dogs (10 cases). Vet Dermatol. 2016 Dec;27(6):488-e131.
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2016-06-16 · Systemic lupus erythematosus (SLE) is an autoimmune disease that can affect many organs, including the skin, joints, the central nervous system and the kidneys. Women of childbearing age and B Cell Receptor Signaling in Human Systemic Lupus Erythematosus - PubMed.

Bullous systemic lupus erythematosus (SLE) is an autoimmune subepidermal blistering disease that occurs in patients with SLE. It can be associated with antibodies against type VII collagen.
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OBJECTIVE: Systemic lupus erythematosus (SLE) is a chronic, relapsing-remitting autoimmune disorder that involves multiple organ systems including the central nervous system. Among the items included in the nomenclature for neuropsychiatric SLE, mood disorders have been identified.

The most common and most severe form is systemic lupus erythematosus. Cutaneous lupus erythematosus is classified into acute, subacute, chronic and intermittent lupus erythematosus [ 11, 12 ].